Liquid-State Drive: A Case for DNA Block Device for Enormous Data

Jiahao Zhou, Mingkai Dong, Fei Wang, Jingyao Zeng, Lei Zhao, Chunhai Fan, Haibo Chen
Institute of Parallel and Distributed Systems, SEIEE, Shanghai Jiao Tong University
School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, National Center for Translational Medicine, Shanghai Jiao Tong University

Abstract

The rapid development of DNA synthesis and sequencing technologies is making the ultra-high-density storage medium DNA to meet the rising demand for enormous data storage. The block storage interface, which is massively employed in storage systems, is the critical abstraction to integrate DNA storage into silicon-based computer systems. In this paper, we explore building block devices on DNA and identify the challenges of petabyte-scale metadata management and high DNA access costs. We propose a holistic DNA block device design called LIQUID-STATE DRIVE to provide low-cost block access to exabyte-scale data with the help of small yet fast SSDs. We adopt the dual-layer translation table to leverage SSDs to decrease the metadata updating cost. We introduce symbiotic metadata and delayed invalidation to reduce the cost of garbage collection and block updating. Our evaluation demonstrates that in microbenchmarks and real-world traces, the write cost reduces up to seven orders of magnitude and 2, 927×, and the read cost reduces up to 6, 206×and 7×, respectively. We expect our exploration and experience in building DNA block devices to be useful in expediting the advancement of DNA storage and bridging the gap between information technology and biotechnology.

Overview of LiqSD
Overview of LiqSD

Contact Information

Please contact Jiahao Zhou or Mingkai Dong for further information. Welcome to let us know about bug reports and suggested improvements, while we may not be able to provide technical support timely.